Table 3.
Mean changes in anthropometric, body composition, bone mass, muscle strength, and physical function measures from baseline to 6-month followup by intervention group.
| Physical Activity + Weight Loss (N = 19) | Physical Activity + Successful Aging (N = 13) | |||
|---|---|---|---|---|
| Mean change (BL-6FU) | P-value | Mean change (BL-6FU) | P-value | |
| Anthropometric | ||||
| Waist circumference, cm | −4.0 (7.5)# | .03 | −1.1 (5.2) | .50 |
| Body weight, kg | −4.9 (4.8)§ | <.001 | −1.0 (3.5)§ | .44 |
| BMI, kg/m2 | −1.7 (1.7)§ | <.001 | −0.4 (1.3)§ | .46 |
| DXA | ||||
| Percent body fat | −2.4 (1.9)§ | <.001 | −0.05 (1.3)§ | .67 |
| Total fat mass, kg | −4.4 (3.2)§ | <.001 | −0.6 (2.1)§ | .27 |
| Total lean mass, kg | −1.5 (1.7) | .001 | −0.7 (1.4) | .08 |
| Appendicular lean mass, kg | −0.9 (0.8) | .001 | −0.5 (1.1) | .06 |
| Total body BMD, g/cm2 | −0.010 (.032) | .18 | −0.006 (.026) | .41 |
| Total hip BMD, g/cm2 | −0.002 (.032) | .72 | 0.005 (.014) | .17 |
| Abdominal CT | ||||
| Total fat, cm2 | −75.1 (94.4)§ | <.01 | −5.2 (72.4)§ | .80 |
| Visceral fat, cm2 | −38.1 (40.4)§ | <.01 | −5.5 (26.2)§ | .46 |
| Subcutaneous fat, cm2 | −37.0 (62.8) | .02 | −0.4 (55.9) | .84 |
| Right thigh CT | ||||
| Total fat, cm2 | −18.1 (17.5) | <.01 | −5.4 (9.9) | .07 |
| Subcutaneous, cm2 | −15.4 (14.8) | <.01 | −4.8 (9.5) | .09 |
| Muscle mass, cm2 | −2.3 (4.0)§ | .03 | 1.5 (3.7)§ | .13 |
| Muscle density, HU | 1.3 (1.2) | <.01 | 0.9 (1.2) | .02 |
| Lean muscle mass, cm2 | 1.7 (4.0) | .08 | 2.8 (4.2) | .04 |
| Right quadriceps CT | ||||
| Muscle mass, cm2 | −1.6 (2.4) | .02 | −1.4 (3.9) | .31 |
| Muscle density, HU | 1.3 (3.7) | <.01 | 1.0 (1.4) | .03 |
| Lean muscle mass, cm2 | −0.17 (2.2) | .54 | −0.41 (3.5) | .79 |
| Specific torque, N·m/cm2 | −0.24 (0.58) | .11 | −0.001 (0.31) | .99 |
| Knee extensor strength | ||||
| Peak torque, N·m | −16.8 (27.9) | .01 | −2.5 (17.2) | .91 |
| Average torque, N·m | −14.0 (22.0) | .01 | −3.3 (13.5) | .45 |
| SPPB score | 0.7 (1.4) | .04 | 0.5 (0.9) | .13 |
#± Standard deviation.
§Denotes a significant difference between intervention programs, P < .05.