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Clot volume. Preheparinziation, using both full (titrated to activated clotting time > 300 seconds) and low (5000-IU bolus) doses, was associated with a significant decrease in clot volume. Open CO2 EVH without preheparinization produced a similar reduction. When clot was present in preheparinized or open CO2 EVH veins, it was normally of trivial volume (B, arrowhead) compared with the substantial volumes imaged in the unheparinized control group (A, arrowhead).
