Figure 2.

Cytoplasmic localization of L1-ORF1p in human tumors. The following tissues were stained with L1-ORF1p antisera: (A) Healthy prostate, colon, kidney, and spleen samples, none of which stain significantly for L1-ORF1p, thus revealing the specificity of the L1-ORF1p antisera; (B) tumors originating from human bladder tissue, with the first panel displaying a tumor that does not stain for L1-ORF1p and the other two panels staining strongly for cytoplasmic L1-ORF1p; (C) two prostate tumors, in which the left panel does not stain but the right panel stains for cytoplasmic L1-ORF1p; (D) two colorectal tumors, the first of which does not stain for L1-ORF1p whereas the other stains for cytoplasmic L1-ORF1p.