Table 5. Penetrance values for combinations of genotypes from five SNPs exhibiting interactions in the absence of independent main effects.
CC | Cc | cc | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
AA | Aa | aa | AA | Aa | aa | AA | Aa | aa | |||
EE | DD | BB | 0.6 | 0.6 | 0.0 | 0.1 | 1.0 | 1.0 | 0.1 | 1.0 | 0.0 |
Bb | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.0 | 0.3 | 0.9 | ||
bb | 1.0 | 0.1 | 0.0 | 0.9 | 1.0 | 0.0 | 0.0 | 0.1 | 1.0 | ||
Dd | BB | 1.0 | 1.0 | 0.0 | 0.0 | 1.0 | 1.0 | 0.8 | 0.1 | 1.0 | |
Bb | 0.0 | 1.0 | 0.9 | 0.0 | 0.0 | 0.9 | 0.0 | 1.0 | 0.9 | ||
bb | 1.0 | 0.1 | 0.0 | 0.4 | 0.9 | 1.0 | 1.0 | 0.9 | 0.1 | ||
dd | BB | 0.9 | 0.8 | 0.4 | 1.0 | 0.0 | 1.0 | 0.1 | 0.0 | 0.0 | |
Bb | 0.3 | 1.0 | 0.0 | 1.0 | 0.8 | 0.0 | 0.0 | 1.0 | 0.0 | ||
bb | 1.0 | 0.9 | 0.0 | 0.1 | 0.0 | 0.1 | 0.0 | 0.1 | 0.0 | ||
Ee | DD | BB | 1.0 | 0.0 | 1.0 | 0.8 | 0.9 | 0.0 | 0.0 | 0.0 | 0.0 |
Bb | 0.5 | 1.0 | 0.0 | 0.7 | 1.0 | 0.8 | 1.0 | 0.1 | 0.1 | ||
bb | 1.0 | 0.0 | 0.2 | 0.0 | 1.0 | 1.0 | 0.3 | 0.0 | 1.0 | ||
Dd | BB | 0.0 | 1.0 | 0.0 | 0.1 | 0.0 | 0.9 | 0.0 | 0.9 | 1.0 | |
Bb | 1.0 | 0.9 | 0.0 | 1.0 | 0.0 | 1.0 | 1.0 | 0.1 | 1.0 | ||
bb | 0.0 | 0.7 | 1.0 | 0.9 | 0.0 | 0.3 | 0.1 | 0.0 | 0.9 | ||
dd | BB | 1.0 | 0.9 | 0.4 | 0.8 | 0.1 | 0.0 | 1.0 | 0.1 | 0.0 | |
Bb | 0.2 | 0.2 | 0.2 | 1.0 | 0.0 | 0.1 | 0.9 | 0.9 | 0.0 | ||
bb | 0.0 | 1.0 | 0.5 | 0.0 | 1.0 | 0.4 | 0.9 | 1.0 | 0.0 | ||
ee | DD | BB | 0.8 | 1.0 | 1.0 | 0.1 | 1.0 | 0.9 | 0.9 | 1.0 | 0.1 |
Bb | 0.7 | 0.0 | 0.2 | 0.8 | 0.0 | 1.0 | 0.9 | 0.1 | 0.9 | ||
bb | 0.1 | 0.0 | 0.1 | 1.0 | 0.2 | 0.7 | 0.0 | 0.4 | 1.0 | ||
Dd | BB | 0.0 | 0.0 | 1.0 | 0.0 | 1.0 | 1.0 | 0.1 | 0.0 | 0.1 | |
Bb | 0.9 | 0.2 | 0.0 | 0.0 | 1.0 | 0.0 | 0.1 | 0.0 | 0.9 | ||
bb | 0.0 | 1.0 | 1.0 | 0.3 | 0.9 | 0.0 | 1.0 | 0.0 | 1.0 | ||
dd | BB | 0.0 | 0.1 | 0.9 | 0.0 | 1.0 | 0.0 | 1.0 | 0.8 | 1.0 | |
Bb | 0.6 | 0.1 | 0.0 | 0.0 | 1.0 | 0.0 | 1.0 | 1.0 | 0.8 | ||
bb | 0.1 | 1.0 | 1.0 | 0.0 | 1.0 | 0.9 | 0.0 | 1.0 | 1.0 |