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Flow cytometry analysesa
| Prime | % of IFN-γ+ CD8+ cells over total CD8+ cells |
||
|---|---|---|---|
| No boost | AdC68E7E6E5 | AdC68gD-E7E6E5 | |
| None | >0.1 | >0.1 | 21.9 |
| pE7E6E5 | >0.1 | >0.1 | 21.2 |
| pgD-E7E6E5 | 0.3 | 2.5 | 47.4 |
Analyses of IFN-γ-secreting E7-specific CD8+ T-cell precursors in mice submitted to heterologous prime-boost immunizations using the pE7E6E5 or pgD-E7E6E5 DNA vector and the AdC68E7E6E5 or AdC68gD-E7E6E5 adenovirus vector.
