TABLE 1.
Specificity of individual Plasmodium MSP1-p19 enzyme immunoassaysa
| Antigen | No. of normal U.S. donors tested | IR (S/N ratio > 5.0) | RR (S/N ratio > 5.0) | Specificity (%) |
|---|---|---|---|---|
| P. ovale MSP1-p19 | 500 | 0 | 0 | 100 |
| P. vivax MSP1-p19 | 500 | 6 | 5 | 99.0 |
| P. falciparum MSP1-p19 | 500 | 0 | 0 | 100 |
| P. malariae MSP1-p19 | 500 | 3 | 0 | 100 |
a
Initial reactive rates (IR) were determined by testing normal blood donors from the United States in singlicate. Initial reactives were retested in duplicate; specimens with a mean S/N ratio > 5.0 or greater were considered to represent repeat reactives (RR). Two of the five P. vivax MSP1-p19 repeat reactives were positive by the Lab 21 Healthcare antibody ELISA.