TABLE 3.

Plasmodium MSP1-p19 IgG and IgM antibodies in experimentally infected chimpanzees

Animal	Infection	Species-specific IgG titer determined by IFA				S/N ratioa
						P. falciparum		P. vivax		P. ovale		P. malariae
		P. falciparum 3D7	P. vivax SalI	P. malariae	P. ovale	IgG	IgM	IgG	IgM	IgG	IgM	IgG	IgM
Heppie	P. malariae	≥16,384	≥16,384	≥16,384	≥16,384	1.3	10.1	7.3	93.4	5.3	20.1	67.8	109.1
Foxy	P. ovale	1,024	4,096	1,024	≥16,384	1.0	7.3	1.0	6.2	13.4	109.1	1.3	45.1
Jeanie	P. ovale	256	≥16,384	256	≥16,384	2.8	4.5	2.5	2.7	2.3	69.2	0.9	13.0
Marietta	P. ovale	1,024	≥16,384	1,024	≥16,384	1.1	2.0	1.1	4.9	22.6	109.1	0.9	24.5
Merv	P. ovale	256	≥16,384	1,024	4,096	107.1	74.6	107.1	98.8	131.1	109.1	67.8	109.1
Amanda	P. vivax	256	≥16,384	256	≥16,384	1.0	5.0	25.2	107.1	1.0	10.2	0.8	16.4
Arthur	P. vivax	4,096	≥16,384	1,024	≥16,384	0.8	6.9	44.9	107.1	1.5	29.5	1.5	47.5
Brandy	P. vivax	64	≥16,384	16	≥16,384	1.0	1.7	1.0	16.7	1.0	3.2	0.7	3.8
Brodie	P. vivax	64	≥16,384	64	≥16,384	1.0	8.8	19.1	107.1	1.5	7.1	0.9	7.3
Callie	P. vivax	256	≥16,384	64	≥16,384	0.9	1.7	14.5	107.1	0.9	5.0	1.1	20.5
Edwina	P. vivax	256	4,096	64	≥16,384	0.8	3.8	3.1	103.0	0.8	3.2	0.7	32.0
Luther	P. vivax	64	4,096	64	256	1.1	2.2	12.8	107.1	0.7	4.4	0.6	11.0
Mary	P. vivax	4,096	≥16,384	1,024	≥16,384	1.2	5.1	107.1	107.1	131.1	83.3	5.6	7.1
Patrick	P. vivax	4,096	≥16,384	1,024	≥16,384	1.1	11.1	34.2	107.1	1.4	18.4	1.0	32.3

^aSamples exhibiting an S/N ratio ≥ 5.00 (IgG assays) and S/N ratio ≥ 10.0 (IgM assays) were considered antibody positive.