TABLE 5.

Pan-Plasmodium MSP-19 IgG antibodies among blood smear- and IFA antibody-positive human malaria patients^a

Sample	Species	IFA	Commercial ELISA S/CO	Pan-malaria MSP1-p19 EIA S/N ratio
Pv-1	P. vivax	P. vivax	2.41	58.35
Pv-2	P. vivax	P. vivax	19.20	65.93
Pv-5	P. vivax	P. vivax, P. ovale	19.20	65.93
Pv-9	P. vivax	P. vivax, P. ovale	19.20	65.93
Pv-10	P. vivax	P. vivax	4.82	47.27
Pv-11	P. vivax	P. vivax, P. ovale	19.20	65.93
Pv-12	P. vivax	P. vivax	6.69	37.62
Pv-14	P. vivax	P. vivax, P. falciparum	19.20	65.93
Pf-6	P. falciparum	P. falciparum	19.20	65.93
Pf-16	P. falciparum	P. falciparum	12.02	8.51
Pf-17	P. falciparum	P. vivax, P. falciparum, P. ovale	19.20	20.27
Pf-18	P. falciparum	P. vivax, P. falciparum	19.20	12.76
Pm-2	P. malariae	P. malariae	0.29	65.93
Pm-15	P. malariae	P. falciparum, P. malariae	0.88	5.11
Po-1	P. ovale	P. falciparum, P. ovale	14.49	65.93
Po-19	P. ovale	P. vivax, P. ovale	19.20	65.93
Po-20	P. ovale	P. ovale	0.43	2.64b
Po-21	P. ovale	P. vivax, P. ovale	16.78	65.93
Po-23	P. ovale	P. falciparum, P. ovale	16.54	65.93
Po-24	P. ovale	P. ovale	13.88	55.35
Po-25	P. ovale	P. ovale	0.37	23.47
Po-26	P. ovale	P. ovale	0.88	32.37

^aData represent EIA results obtained using beads cocoated with four MSP1-p19 recombinant proteins. The species column entries represent Plasmodium species identified by microscopic examination of blood smears. The IFA column entries represent those species detected with an antibody titer greater than 1:256. Samples exhibiting an S/N ratio ≥ 5.00 are considered antibody positive.

^bS/N ratio of 11.5 using P. ovale MSP1-p19 antigen-only EIA.