FIG. 2.

Hmt1 influences the cotranscriptional recruitment of U1 snRNP and its associated proteins. ChIP-chip was used to assess the effects of Hmt1 on the cotranscriptional recruitment of U1 snRNP and its associated proteins, which are Snp1 (A), Prp40 (B), and Mud2 (C). The impact of Hmt1 was assessed as the change in the percentage of intron-containing genes (ICGs) within the total number of genes bound by a splicing factor, as denoted by the bar graphs on the left. The total numbers of non-ICGs bound by each factor are shown by the middle bar graphs, and the total numbers of ICGs bound by each splicing factor are shown by the bar graphs on the right. The wild-type ChIP-chip data for Prp40 and Mud2 were obtained from Moore et al. (47).