TABLE 7.
Gene product | mRNA expression |
Expression ratio |
Double-sided P value | ||||
---|---|---|---|---|---|---|---|
Fli1wt/wt |
Fli1ΔCTA/ΔCTA |
||||||
Mean | SD | Mean | SD | ΔCTA/wt | wt/ΔCTA | ||
gpIIb | 6.6 | 0.57 | 2.2 | 0.7 | 0.33 | 3 | 0.001 |
gpV | 4.4 | 0.09 | 1.9 | 0.05 | 0.43 | 2.32 | 0.0001 |
gpIX | 7.4 | 1.14 | 2.1 | 0.3 | 0.28 | 3.52 | 0.003 |
CD41 | 2.43 | 0.45 | 2.35 | 0.16 | 0.97 | 1.03 | 0.787 |
CD61 | 0.49 | 0.17 | 0.11 | 0.04 | 0.22 | 4.45 | 0.019 |
P-Selectin | 0.57 | 0.05 | 0.56 | 0 | 0.98 | 1.02 | 0.67 |
PECAM-1 | 4.76 | 1.13 | 1.65 | 0.37 | 0.35 | 2.88 | 0.011 |
NFE2 | 3.7 | 0.14 | 1.4 | 0.13 | 0.38 | 2.64 | 0.005 |
Rab27B | 4.03 | 0.22 | 1.91 | 0.18 | 0.47 | 2.11 | 0.011 |
MAFK | 1.89 | 0.38 | 2.23 | 0.24 | 1.18 | 0.85 | 0.027 |
MAFG | 4.73 | 0.61 | 1.69 | 0.52 | 0.36 | 2.80 | 0.043 |
RUNX1 | 2.76 | 0.51 | 2.38 | 0.71 | 0.86 | 1.16 | 0.634 |
Tubulin B1 | 0.24 | 0.04 | 2.23 | 0.19 | 9.29 | 0.11 | 0.003 |
PU1 | 2.11 | 0.14 | 2 | 0.3 | 0.95 | 1.06 | 0.6 |
GATA-1 | 1.23 | 0.2 | 1.03 | 0.09 | 0.84 | 1.19 | 0.3 |
c-mpl | 0.78 | 0.18 | 0.35 | 0.1 | 0.45 | 2.23 | 0.038 |
ITGB1 | 7.98 | 1.14 | 2.32 | 0.45 | 0.29 | 3.44 | 0.02 |
PF4 | 0.83 | 0.03 | 0.41 | 0.001 | 0.5 | 2.02 | 0.05 |
Fli1 | 0.38 | 0.07 | 0.39 | 0.09 | 1.03 | 0.97 | 0.92 |