TABLE 2.
Distribution of the cagA gene and of the vacA and iceA alleles in isolates of H. pylori deriving from patients with different clinical manifestations
| Genotype | % with clinical manifestation (no. affected/total no. of samples) |
|
|---|---|---|
| Enanthematous gastritis | Erosive gastritis | |
| cagA genesa | ||
| cagA positive | 42.3 (11/26) | 57.7 (15/26) |
| cagA negative | 64.3 (9/14) | 35.7 (5/14) |
| vacA genesb | ||
| vacAs1a/m1 | 20.0 (1/5) | 80.0 (4/5) |
| vacAs1b/m1 | 50.0 (4/8) | 50.0 (4/8) |
| vacAs1a/m2 | 40.0 (2/5) | 60.0 (3/5) |
| vacAs1b/m2 | 33.3 (2/6) | 66.7 (4/6) |
| vacAs2/m2 | 80.0 (8/10) | 20.0 (2/10) |
| vacAs1b/m1m2 | 66.7 (2/3) | 33.3 (1/3) |
| vacAs2/m1m2 | 50.0 (1/2) | 50.0 (1/2) |
| vacA negative | 100.0 (1/1) | |
| iceA genesc | ||
| iceA1 + iceA2 | 100.0 (2/2) | |
| iceA1 | 33.3 (3/9) | 66.7 (6/9) |
| iceA2 | 57.1 (16/28) | 42.9 (12/28) |
| iceA negative | 100.0 (1/1) | |
a
P = 0.185.
b
P = 0.350.
c
P = 0.047.