TABLE 2.
In vitro activities of 8 antifungal agents against terbinafine-resistant and -sensitive strains of T. rubruma
| Type of T. rubrum strain (no. of strains tested) | Antifungal agent | Mean IZD ± SE (mm) | IZD range (mm) |
|---|---|---|---|
| Terbinafine resistant (5) | Ketoconazole | 50.53 ± 10.85 | 20-74 |
| Miconazole | 41.53 ± 10.88 | 25-60 | |
| Itraconazole | 41.67 ± 8.99 | 34-60 | |
| Terbinafine | 0 | 0 | |
| Fluconazole | 51.13 ± 11.61 | 35-70 | |
| Griseofulvin | 49.07 ± 8.92 | 33-60 | |
| Ciclopirox olamine | 37.27 ± 4.45 | 32-48 | |
| Voriconazole | 63.00 ± 9.43 | 52-80 | |
| Terbinafine sensitive (5) | Ketoconazole | 30.13 ± 10.09 | 20-50 |
| Miconazole | 29.80 ± 7.34 | 20-45 | |
| Itraconazole | 34.80 ± 5.32 | 30-45 | |
| Terbinafine | 64.33 ± 7.01 | 47-70 | |
| Fluconazole | 19.40 ± 17.55 | 0-50 | |
| Griseofulvin | 41.00 ± 8.68 | 30-55 | |
| Ciclopirox olamine | 35.47 ± 1.96 | 32-40 | |
| Voriconazole | 51.67 ± 8.24 | 35-65 |
a
Each drug testing was performed with fresh inoculum in triplicate on three different days.