TABLE 2.
Nucleotide variations in HSV-2 UL23 detected in this study
| Nucleotidea | Amino acida | No. of strains (of 68) in which variant was detected | Frequency of rare allele (%) |
|---|---|---|---|
| Previously detected variants | |||
| G116A | G39E | 58 | 14.7b |
| A232G | N78D | 31 | 45.6 |
| G420T | L140F | 11 | 16.2 |
| G79A | A27T | 3 | 4.4 |
| G643A | A215T | 2 | 2.9 |
| C476T | T159I | 1 | 1.5 |
| T85G | S29A | 1 | 1.5 |
| Newly detected variants | |||
| T90C | NCc | 5 | 7.4 |
| A660G | NC | 5 | 7.4 |
| C783T | NC | 3 | 4.4 |
| G207A | NC | 2 | 2.9 |
| A307G | N103D | 2 | 2.9 |
| G449A | G150D | 2 | 2.9 |
| C582T | NC | 2 | 2.9 |
| C52T | R18C | 1 | 1.5 |
| C87T | NC | 1 | 1.5 |
| G183T | NC | 1 | 1.5 |
| G199A | A67T | 1 | 1.5 |
| A256C | M86L | 1 | 1.5 |
| G286A | E96K | 1 | 1.5 |
| C471A | NC | 1 | 1.5 |
| C493G | H165D | 1 | 1.5 |
| T565C | NC | 1 | 1.5 |
| T621C | NC | 1 | 1.5 |
| C663A | NC | 1 | 1.5 |
| C682A | L228I | 1 | 1.5 |
| C729T | NC | 1 | 1.5 |
| C787T | NC | 1 | 1.5 |
| C811A | P271T | 1 | 1.5 |
| C842G | S281C | 1 | 1.5 |
| C895T | NC | 1 | 1.5 |
| C942T | NC | 1 | 1.5 |
| G1013A | R338Q | 1 | 1.5 |
| G1039A | G347R | 1 | 1.5 |
| A1063G | T355A | 1 | 1.5 |
| C1068T | NC | 1 | 1.5 |
| C1101T | NC | 1 | 1.5 |
| A1125C | NC | 1 | 1.5 |
a
The nucleotide and amino acid in strain HG52 (10) is listed before the relevant position in the HG52 sequence, followed by the sequence detected in this study.
b
The rare allele, G at position 116, was present in the prototype HG52 strain.
c
NC, noncoding variation.