FIG. 1.
Correlation between sensitivity of IS2404 PCR (a) and microscopy (MIC) (b) and duration of disease among 79 laboratory-confirmed BUD patients (35 nonulcerative lesions and 44 ulcerative lesions) without previous antimycobacterial treatment. The analysis includes swabs (from ulcerative lesions), FNA samples, and punch biopsy specimens (from ulcerative and nonulcerative lesions). The patients were divided into four groups according to duration of disease (1 to 14 days, 15 to 59 days, 60 to 149 days, and ≥150 days). Due to a sample size of <5, calculation of the sensitivity of microscopy for punch biopsy specimens was not possible (b). Linear trends in proportions are shown as coefficient of determination (R2) for PCR (R2swab, 0.42; R2FNA, <0.01; R2punch, 0.09) and for microscopy (R2swab, 0.63; R2FNA, 0.77; R2punch, 0.99).