TABLE 1.
Origin, MICs determined by Etest, and genotypes based on partial (gdh gene) or full multilocus sequence typing (MLST) and pulsed-field gel electrophoresis (PFGE) of 33 E. faecalis isolates from bloodstream infections in the North Denmark region in 2007
| Strain ID | Site of infectiona | Originb | Hospitalc | Etest MIC (μg/ml) ford: |
MLST |
PFGE profile | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| AMP | PEN | IPM | GEN | VAN | gdh | ST | |||||
| Isolates with reduced susceptibility to penicillin | |||||||||||
| B69486 | AVP | C | 4 | 1.5 | >32 | 6 | >1024 | 3 | 12 | 6 | A1 |
| B135456 | Urinary tract | N | 6 | 4 | >32 | 8 | 96 | 2 | 12 | 6 | A1 |
| B33621 | Urinary tract | N | 7 | 1 | 16 | 8 | 1024 | 3 | 12 | 6 | A1 |
| B37814 | Undetermined | N | 8 | 1.5 | >32 | 8 | >1024 | 3 | 12 | 6 | A1 |
| B63792 | Urinary tract | NH | 8 | 1.5 | >32 | 6 | >1024 | 4 | 12 | 6 | A1 |
| B71580 | HBP tract | HC | 8 | 1.5 | >32 | 8 | >1024 | 4 | 12 | 6 | A1 |
| B98380 | Undetermined | C | 1 | 3 | 16 | 4 | >1024 | 2 | 12 | 6 | A2 |
| B15725 | Undetermined | N | 8 | 1.5 | 32 | 32 | >1024 | 3 | 12 | 6 | A2 |
| B72715 | Urinary tract | N | 4 | 2 | >32 | 6 | 1024 | 3 | 12 | 6 | A3 |
| B37093 | Undetermined | N | 8 | 1 | >32 | 4 | >1024 | 3 | 12 | 6 | A3 |
| B33672 | Perirenal abscess | N | 3 | 1 | 32 | 4 | 1024 | 3 | 12 | 6 | A4 |
| B54027 | IV catheter | N | 8 | 3 | >32 | 6 | >1024 | 3 | 12 | 6 | A4 |
| B147794 | Diabetic gangrene | N | 8 | 0.75 | >32 | 4 | >1024 | 2 | 12 | 6 | A4 |
| B110274 | Undetermined | N | 8 | 3 | >32 | 4 | >1024 | 3 | 12 | 6 | A5 |
| B85040 | Urinary tract | HC | 8 | 1.5 | 16 | 4 | >1024 | 3 | 12 | 6 | A6 |
| B67010 | Endocarditis | N | 8 | 1.5 | >32 | 8 | >1024 | 3 | 12 | 6 | A7 |
| B37957 | Surgical wound | N | 8 | 1.5 | >32 | 6 | >1024 | 3 | 12 | 6 | A8 |
| B84847 | HBP tract | N | 5 | 1.5 | >32 | 2 | 16 | 3 | 2 | 23 | NDe |
| B56765 | Undetermined | N | 8 | 4 | >32 | 32 | >1024 | 4 | 4 | 28 | ND |
| B16457 | Undetermined | N | 8 | 4 | 32 | 8 | 96 | 4 | New | New | ND |
| Isolates with full susceptibility to penicillin | |||||||||||
| B84828 | HBP tract | N | 2 | 2 | 4 | 2 | 16 | 3 | 12 | New | ND |
| B115329 | Abdomen | N | 4 | 2 | 3 | 2 | 24 | 2 | 12 | New | ND |
| B104838 | Urinary tract | N | 8 | 2 | 2 | 2 | 12 | 3 | 1 | ND | ND |
| B56478 | Urinary tract | C | 3 | 1.5 | 4 | 1.5 | 64 | 3 | 3 | ND | ND |
| B96280 | Urinary tract | N | 8 | 1 | 1 | 2 | 12 | 3 | 3 | ND | ND |
| B30537 | Undetermined | HC | 8 | 1.5 | 4 | 2 | >1024 | 3 | 5 | ND | ND |
| B150692 | Endocarditis | N | 8 | 0.5 | 1.5 | 3 | 16 | 3 | 5 | ND | ND |
| B126859 | Urinary tract | N | 4 | 3 | 6 | 2 | 16 | 3 | 7 | ND | ND |
| B70401 | Biliary tract | N | 8 | 2 | 12 | 2 | 48 | 4 | 7 | ND | ND |
| B123830 | IV catheter | N | 8 | 3 | 3 | 2 | 24 | 4 | 7 | ND | ND |
| B75968 | Undetermined | HC | 7 | 1.5 | 2 | 2 | 48 | 3 | 16 | ND | ND |
| B28054 | Pancreas | N | 8 | 1 | 6 | 2 | 48 | 3 | 20 | ND | ND |
| B128229 | Surgical wound | N | 8 | 3 | 12 | 1.5 | 24 | 4 | 27 | ND | ND |
a
AVP, aorthic vascular prosthesis; HBP, hepato-biliary-pancreatic.
b
N, nosocomial onset; C, community onset; HC, healthcare associated; NH, nursing home associated.
c
1, Brovst Hospital; 2, Dronninglund Hospital; 3, Farsø Hospital; 4, Frederikshavn Hospital; 5, Hjørring Hospital; 6, Hobro Hospital; 7, Aalborg Hospital section North; 8, Aalborg Hospital section South.
d
AMP, ampicillin; PEN, penicillin; IPM, imipenem; GEN, gentamicin; VAN, vancomycin.
e
ND, not determined.