FIG. 3.

Both IFN-α and IFN-λ are secreted by pDCs following influenza A infection. BMDCs cultured with FLT-3 ligand were mock infected or infected with WSN (live or UV inactivated) at an MOI of 1 or treated with CpG (2 μg/ml). At 24 h postinfection, the DC supernatants were assayed by ELISA for the presence of IFN-λ (A) or IFN-α (B) protein. Data represent the means and standard deviations of results from three replicate samples.