FIG. 8.

Efficient infection of HAE by HCoV-HKU1 does not require HLA-C. Replication kinetics of HCoV-HKU1 were assessed by real-time RT-PCR of RNA present in apical washes from HCoV-HKU1-infected HAE cultures pretreated with either no antibody (yellow), HLA-C-specific antibody (blue), HLA-BC antibody (pink), a combination of the antibodies (green), or ACE2 antibody (black). Titers are represented by virus copies per milliliter. No significant differences in HCoV-HKU1 infection and replication were measured in any treatment group. n = 3 for each treatment group.