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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Synthesis (Stuttg). 2010 Jun 1;2010(11):1804–1821. doi: 10.1055/s-0029-1218742

Table 7.

One-pot procedure for the Balz-Schiemann reaction.

graphic file with name nihms197279u7.jpg
R NOBF4 reaction (%) Traditional method
H 72 60
2-Cl 90 40
2-COMe 56 47
4-CH2COOH 73 failed
2-OH 58 failed