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(A) Overlay of the average structures of rIAPP1–19 (blue) and hIAPP1–19 (red). The average of the 20 structures of each peptide was aligned using the STAMP algorithm present in the Multiseq utility in VMD (54, 55). (B) View of rIAPP1–19 and hIAPP1–19 viewed end-on from the N-terminus. (C) View of rIAPP1–19 showing the curve in the helical region. (D) View of hIAPP1–19 showing the absence of a curve in the helical region.
