Table 3. [3H]SR141716a Saturation Binding.
Bmax (fmol/mg) |
Kd (nM) |
|||
---|---|---|---|---|
WT | GASP1 KO | WT | GASP1 KO | |
Spinal cord | ||||
Vehicle | 712±82 | 438±31 | 1.9±0.5 | 0.9±0.2 |
WIN55,212-2 | 404±28 | 375±26 | 1.2±0.2 | 1.1±0.2 |
Cerebellum | ||||
Vehicle | 1664±144 | 1613±111 | 1.5±0.3 | 1.3±0.2 |
WIN55,212-2 | 1379±92 | 1840±93 | 1.6±0.3 | 1.5±0.2 |