Table I.
Nuclear migration defects at the start of migration
Genotype | Defectsa |
µm | |
Wild type | 3.3 ± 0.2 (36) |
unc-83(e1408) | 0.05 ± 0.05 (21) |
unc-84(n369) | 0.06 ± 0.03 (20) |
klc-2(km11) | 0.3 ± 0.1 (26) |
nud-2(ok949) | 3.2 ± 0.3 (36) |
nud-2(ok949);bicd-1(RNAi) | 3.3 ± 0.3 (36) |
unc-83(e1408);klc-2::KASH | 3.1 ± 0.2 (20) |
Start migration (20 of 42)b | |
unc-83(e1408);klc-2::KASH | 0.05 ± 0.03 (22) |
No migration (22 of 42)b |
The mean distance ± SEM nuclei migrated in the first 10 min after the completion of intercalation of that cell. The sample size in number of nuclei is in parentheses.
42 nuclei were filmed in the unc-83(e1408);klc-2::KASH strain. 20 of them began nuclear migration at a normal time, and the rest failed to migrate.