Figure 1.
Ribonuclease L competitive inhibitor RNA (RNase L ciRNA) from the ORF of poliovirus. (A) Diagram of the RNA structure in the poliovirus ORF associated with the competitive inhibition of RNase L; as predicted by M-Fold and Kinefold.2,3,5,6 Putative loop E motif highlighted in green. Putative H-H type kissing loop interaction highlighted in light blue. (B) Loop E motif from X. laevis 5S rRNA (adapted from Leontis and Westhof).7