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. 2010 Oct 12;5(10):e13267. doi: 10.1371/journal.pone.0013267

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Liu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Demethylation (%) of FOXP3 was measured with real-time PCR. CD4⁺CD25^hi T-cells (% in lymphocytes) were measured with flow cytometry. A. Correlation between FOXP3 demethylation and unstimulated CD4⁺CD25^hi T-cells (%). B. Correlation between FOXP3 demethylation and LpA-activated CD4⁺CD25^hi T-cells (%). N = 20/24; correlation was analyzed with Pearsons correlation coefficient.