Table 2. Treatment categories, Drug dosages and definitions of treatment outcomes.
1: Treatment categories and regiments | |||
Treatment category | Type of patients | Treatment regimens*** | |
Intensive Phase | Continuation phase | ||
Category 1 | New sputum smear-positive PTB | 2(H3R3Z3E3) | 4(H3R3) |
New sputum smear-negative PTB, seriously ill* | |||
New extra-PTB, seriously ill* | |||
Category 2 | Sputum smear-positive relapse | 2(H3R3Z3E3S3)+1(H3R3Z3E3) | 5(H3R3E3) |
Sputum smear-positive treatment failure | |||
Sputum smear-positive treatment after default | |||
Category 3 | New sputum smear-negative, not seriously ill** | 2(H3R3Z3) | 4(H3R3) |
New extra-PTB, not seriously ill** |
*In children, seriously ill sputum smear-negative PTB includes all forms of sputum smear-negative PTB other than primary complex. Seriously ill EP-TB includes TB meningitis (TBM), disseminated TB, TB pericarditis, TB peritonitis and intestinal TB, bilateral extensive pleurisy, spinal TB with or without neurological complications, genitourinary TB, and bone and joint TB.
**Not seriously ill sputum smear-negative PTB includes primary complex. Not seriously ill EP-TB includes lymph node TB and unilateral pleural effusion.
***Prefix indicates month and subscript indicates thrice weekly.
PC = Product code. PC-13 is yellow coloured and PC-14 is orange coloured. Mg/kg = milligrams per kilogram body weight.
Sputum smears positive TB patient's under-go follow-up sputum examinations at the end of intensive phase and extended intensive phase (if IP extended), 2 months into continuation phase and at the end of treatment.