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. 2010 Oct 12;5(10):e13338. doi: 10.1371/journal.pone.0013338

Table 2. Treatment categories, Drug dosages and definitions of treatment outcomes.

1: Treatment categories and regiments
Treatment category Type of patients Treatment regimens***
Intensive Phase Continuation phase
Category 1 New sputum smear-positive PTB 2(H3R3Z3E3) 4(H3R3)
New sputum smear-negative PTB, seriously ill*
New extra-PTB, seriously ill*
Category 2 Sputum smear-positive relapse 2(H3R3Z3E3S3)+1(H3R3Z3E3) 5(H3R3E3)
Sputum smear-positive treatment failure
Sputum smear-positive treatment after default
Category 3 New sputum smear-negative, not seriously ill** 2(H3R3Z3) 4(H3R3)
New extra-PTB, not seriously ill**

*In children, seriously ill sputum smear-negative PTB includes all forms of sputum smear-negative PTB other than primary complex. Seriously ill EP-TB includes TB meningitis (TBM), disseminated TB, TB pericarditis, TB peritonitis and intestinal TB, bilateral extensive pleurisy, spinal TB with or without neurological complications, genitourinary TB, and bone and joint TB.

**Not seriously ill sputum smear-negative PTB includes primary complex. Not seriously ill EP-TB includes lymph node TB and unilateral pleural effusion.

***Prefix indicates month and subscript indicates thrice weekly.

PC = Product code. PC-13 is yellow coloured and PC-14 is orange coloured. Mg/kg = milligrams per kilogram body weight.

Sputum smears positive TB patient's under-go follow-up sputum examinations at the end of intensive phase and extended intensive phase (if IP extended), 2 months into continuation phase and at the end of treatment.