Table 1.
Transcripts that discriminate among classes
| GenBank accesion |
Gene symbol/ UniGene cluster |
Description | Geometric mean intensities class E4 |
Geometric mean intensities class E3 |
Fold change |
Parametric P-value |
|---|---|---|---|---|---|---|
| NM_003112 | SP4 | Sp4 transcription factor (SP4), mRNA | 1.16 | 1.02 | 1.13 | 0.00001 |
| NM_144597 | C15orf40 | Chromosome 15 open reading frame 40, mRNA | 1.14 | 1.00 | 1.14 | 0.00002 |
| AI798812 | Hs.523978 | cDNA clone IMAGE:2348622 3, mRNA | 1.07 | 0.98 | 1.09 | 0.00004 |
| AV681468 | Hs.164146 | cDNA clone GKAAAF07 5, mRNA | 1.07 | 0.97 | 1.10 | 0.00006 |
| NM_001008395 | LOC389541 | Similar to CG14977-PA, mRNA | 0.91 | 1.04 | 0.88 | 0.00006 |
| NM_002281 | KRT81 | Keratin 81 (KRT81), mRNA | 0.93 | 1.01 | 0.92 | 0.00006 |
| NM_207173 | NPSR1 | Neuropeptide S receptor 1, variant 2, mRNA | 0.92 | 1.00 | 0.92 | 0.00009 |
| AA017152 | Hs.103355 | cDNA clone IMAGE:361525 3, mRNA | 0.93 | 1.01 | 0.92 | 0.00010 |
| CN315248 | Hs.543452 | cDNA 5, mRNA | 1.05 | 0.95 | 1.10 | 0.00012 |
| BM703456 | Hs.528873 | cDNA clone UI-E-CL1-afe-e-04-0-UI 5, mRNA | 1.14 | 1.01 | 1.12 | 0.00013 |
| NM_019896 | POLE4 | Polymerase (DNA-directed), epsilon 4, mRNA | 0.92 | 1.07 | 0.86 | 0.00013 |
| DB230039 | Hs.580513 | cDNA clone TRACH3023310 5, mRNA | 0.94 | 1.02 | 0.92 | 0.00015 |
| NM_001226 | CASP6 | Caspase 6, variant α and β | 1.11 | 0.98 | 1.13 | 0.00018 |
| NM_007358 | MTF2 | Metal response element binding transcription factor 2 |
1.17 | 0.99 | 1.18 | 0.00018 |
| NM_178550 | C1orf110 | Chromosome 1 open reading frame 110, mRNA | 1.10 | 1.01 | 1.10 | 0.00019 |
| NM_139174 | LOC161931 | Nuclear RNA-binding protein-like, mRNA | 0.69 | 0.89 | 0.78 | 0.00019 |
| NM_001546 | ID4 | Inhibitor of DNA binding 4, mRNA | 1.29 | 1.06 | 1.21 | 0.00020 |
| NM_020727 | ZNF295 | Zinc-finger protein 295, mRNA | 1.08 | 0.94 | 1.15 | 0.00020 |
| NM_000337 | SGCD | Sarcoglycan, delta, variant 1, mRNA | 1.20 | 1.06 | 1.13 | 0.00021 |
| NM_147164 | CNTFR | Ciliary neurotrophic factor receptor, variant 1, mRNA |
1.09 | 0.99 | 1.11 | 0.00021 |
| NR_000010 | SNORD4A | Small nucleolar RNA, C/D box 4A | 1.10 | 0.98 | 1.12 | 0.00022 |
| XR_001273 | LOC647357 | PREDICT: similar to CG14980-PB, variant 1, RNA |
1.11 | 1.00 | 1.11 | 0.00022 |
| XM_379203 | LOC348801 | PREDICT: hypothetical protein, variant 1, mRNA |
1.07 | 1.00 | 1.07 | 0.00022 |
| XM_497712 | LOC441907 | PREDICT: similar to 60S ribosomal protein L6, mRNA |
1.07 | 0.97 | 1.10 | 0.00023 |
| NM_015364 | LY96 | Lymphocyte antigen 96, mRNA | 0.84 | 0.97 | 0.87 | 0.00023 |
| BQ003813 | Hs.555565 | cDNA clone IMAGE:5847799 3, mRNA | 0.95 | 1.02 | 0.93 | 0.00024 |
| XR_018067 | LOC441228 | PREDICT: similar to exportin-T, mRNA | 0.89 | 0.99 | 0.90 | 0.00026 |
| BX393727 | Hs.440088 | cDNA clone CS0DC001YP02 5-PRIME, mRNA | 1.05 | 0.94 | 1.11 | 0.00033 |
| XM_926149 | LOC642384 | PREDICT: hypothetical protein LOC642384, mRNA |
1.15 | 1.03 | 1.12 | 0.00035 |
| NM_018433 | JMJD1A | Jumonji domain containing 1A, mRNA | 1.08 | 0.95 | 1.14 | 0.00036 |
| NM_004326 | BCL9 | B-cell CLL/lymphoma 9, mRNA | 1.05 | 0.96 | 1.09 | 0.00038 |
| NM_139168 | SFRS12 | Splicing factor, arginine–serine-rich 12, variant 2, mRNA |
1.10 | 0.97 | 1.14 | 0.00038 |
| NM_004890 | SPAG7 | Sperm-associated antigen 7, mRNA | 0.93 | 1.03 | 0.90 | 0.00040 |
| BF590392 | Hs.542085 | cDNA clone IMAGE:3258165 3, mRNA | 0.95 | 1.03 | 0.91 | 0.00041 |
| NM_016202 | ZNF580 | Zinc-finger protein 580, transcript variant 1, mRNA |
1.10 | 1.01 | 1.08 | 0.00041 |
| AI935042 | Hs.575097 | cDNA clone IMAGE:2328437 3, mRNA | 1.03 | 0.97 | 1.07 | 0.00042 |
| BX089938 | Hs.130107 | cDNA clone IMAGE:1504127, mRNA | 1.05 | 0.96 | 1.10 | 0.00043 |
| NM_080390 | TCEAL2 | Transcription elongation factor A (SII)-like 2, mRNA |
1.06 | 0.99 | 1.07 | 0.00043 |
| XM_496731 | LOC441056 | PREDICT: similar to double homeobox 4c, mRNA |
0.94 | 1.02 | 0.93 | 0.00044 |
| BE439917 | Hs.539307 | HTM1-532F HTM1, cDNA, mRNA | 0.91 | 1.00 | 0.92 | 0.00045 |
| NM_006190 | ORC2L | Origin recognition complex, subunit 2-like, mRNA |
0.94 | 1.01 | 0.93 | 0.00045 |
| NM_000312 | PROC | Protein C, mRNA | 0.98 | 1.06 | 0.92 | 0.00046 |
| NM_079423 | MYL6 | Myosin, light chain 6, transcript variant 2, mRNA |
0.92 | 1.01 | 0.91 | 0.00047 |
| BX093261 | Hs.98049 | cDNA clone IMAGE:753731, mRNA | 0.96 | 1.03 | 0.93 | 0.00047 |
| NM_004146 | NDUFB7 | NADH dehydrogenase 1 β subcomplex, 7, mRNA |
0.95 | 1.03 | 0.92 | 0.00049 |
| NM_030815 | PDRG1 | p53 and DNA damage regulated 1, mRNA | 0.92 | 1.03 | 0.90 | 0.00049 |
| NM_002805 | PSMC5 | Proteasome 26S subunit, ATPase, 5, mRNA | 0.92 | 0.98 | 0.94 | 0.00049 |
| BX476711 | Hs.121070 | cDNA clone DKFZp686M05188 5, mRNA | 1.12 | 0.98 | 1.14 | 0.00051 |
| NM_178867 | SFXN4 | Sideroflexin 4, transcript variant 2, mRNA | 1.05 | 0.96 | 1.09 | 0.00052 |
| NM_153822 | PSMD4 | Proteasome 26S subunit, 4, variant 2, mRNA | 0.90 | 1.00 | 0.90 | 0.00056 |
| XM_938229 | PIAS2 | PREDICT: protein inhibitor of activated STAT- 2, mRNA |
1.09 | 0.96 | 1.14 | 0.00058 |
| NM_002305 | LGALS1 | Lectin, galactoside-binding, soluble, 1, mRNA | 0.65 | 0.84 | 0.78 | 0.00060 |
| NM_022171 | TCTA | T-cell leukemia translocation-altered gene, mRNA |
0.94 | 1.04 | 0.91 | 0.00061 |
| BX115738 | Hs.551137 | cDNA clone IMAGp998D07589, mRNA | 1.05 | 0.97 | 1.08 | 0.00063 |
| XM_940109 | LOC650995 | PREDICT: similar to Golgi autoantigen, golgin subfamily a, 2 |
0.96 | 1.05 | 0.91 | 0.00066 |
| AW016203 | Hs.566210 | cDNA clone IMAGE:2712316 3, mRNA | 0.95 | 1.02 | 0.93 | 0.00067 |
| XM_943679 | WBSCR19 | PREDICT: Williams–Beuren syndrome chromosome 19, variant 4 |
1.11 | 0.98 | 1.14 | 0.00070 |
| NM_145237 | LOC94431 | Similar to RNA polymerase I transcription factor RRN3, mRNA |
1.06 | 0.98 | 1.08 | 0.00071 |
| NM_001012753 | ZNF763 | Zinc-finger protein 763, mRNA | 1.11 | 0.99 | 1.12 | 0.00073 |
| NM_022110 | FKBPL | FK506 binding protein-like (FKBPL), mRNA | 0.95 | 1.03 | 0.93 | 0.00074 |
| NM_012262 | HS2ST1 | Heparan sulfate 2-O-sulfotransferase 1, mRNA | 1.25 | 1.10 | 1.14 | 0.00075 |
| NM_080678 | UBE2F | Ubiquitin-conjugating enzyme E2F (putative), mRNA |
0.90 | 1.01 | 0.89 | 0.00075 |
| NM_003789 | TRADD | TNFRSF1A-associated via death domain, mRNA |
0.80 | 0.89 | 0.89 | 0.00077 |
| NM_005530 | IDH3A | Isocitrate dehydrogenase 3 (NAD+) α, mRNA | 0.77 | 0.87 | 0.88 | 0.00077 |
| NM_001029862 | ANKRD30B | Ankyrin repeat domain 30B, mRNA | 1.16 | 1.01 | 1.16 | 0.00078 |
| AI651118 | Hs.565928 | cDNA clone IMAGE:2304126 3, mRNA | 0.94 | 1.01 | 0.92 | 0.00084 |
| NM_001011537 | FYTTD1 | Forty-two-three domain-containing 1, variant 2, mRNA |
1.05 | 0.98 | 1.07 | 0.00085 |
| NM_004930 | CAPZB | Capping protein (actin filament) Z-line, β, mRNA |
0.92 | 1.04 | 0.89 | 0.00087 |
| NR_003264 | SDHALP1 | Succinate dehydrogenase complex, subunit A | 1.11 | 0.98 | 1.14 | 0.00088 |
| BI561597 | Hs.576019 | cDNA clone IMAGE:5298552 5, mRNA | 0.97 | 1.03 | 0.94 | 0.00092 |
Abbreviation: CLL, chronic lymphocytic leukemia.
Seventy transcripts are significant at the nominal 0.001 level of the univariate test. Sorted by P-value of the univariate test. Class 1: E4; class 2: E3.