Table 1.
Demographic and Clinical Characteristics by PASH Status
| NO (N=8486) | YES (N=579) | p value1 | p value2 | |
|---|---|---|---|---|
| Age at Benign Biopsy | <0.001 | <0.001 | ||
| <45 | 2662 (31.4) | 309 (53.4) | ||
| 45 - 54 | 2360 (27.8) | 203 (35.1) | ||
| 55+ | 3464 (40.8) | 67 (11.6) | ||
| Family History of Breast Cancer | 0.116 | |||
| (missing, n=39) | 37 | 2 | ||
| None | 5625 (66.6) | 360 (62.4) | ||
| Weak | 2014 (23.8) | 153 (26.5) | ||
| Strong | 810 (9.6) | 64 (11.1) | ||
| Indication for Biopsy | <0.001 | 0.005 | ||
| (missing, n=558) | 513 | 45 | ||
| Lump | 4722 (59.2) | 379 (71) | ||
| Mammogram | 3251 (40.8) | 155 (29) | ||
| Epithelial Proliferation | 0.606 | |||
| Non-proliferative | 5643 (66.5) | 394 (68) | ||
| Proliferative without atypia | 2538 (29.9) | 168 (29) | ||
| Atypical hyperplasia | 305 (3.6) | 17 (2.9) | ||
| Lobular Involution | <0.001 | <0.001 | ||
| (missing, n=609) | 604 | 5 | ||
| None | 1481 (18.8) | 98 (17.1) | ||
| Partial (1-74% TDLU) | 4595 (58.3) | 455 (79.3) | ||
| Complete (>75% TDLU) | 1806 (22.9) | 21 (3.7) | ||
| Fibroadenoma | <0.001 | <0.001 | ||
| (missing, n=65) | 62 | 3 | ||
| NO | 6325 (75.1) | 527 (91.5) | ||
| YES | 2099 (24.9) | 49 (8.5) |
1
Values displayed as number (percent). Numbers may not always sum to column totals due to missing values for some subjects. P-values based on chi-square test of significance.
2
P-value from multivariate logistic regression adjusting for age, year of biopsy, indication for biopsy, number of breast biopsies, lobular involution, and fibroadenoma. Only variables univariately significant were included in the multivariate analysis.