Table 2.
Maximal active stress response (mN/mm2) following 30 μM phenylephrine, 0.01 μM urotensin II, and 109 mM K+PSS. Control – Vehicle animals (n=9), UTII − 4 week administration of urotensin II (n=6); VO − 4 week volume overload (n=5); VO+UTII − 4 week VO + 4 week UTII administration (n = 4). Data are reported as mean ± sem
| Groups | PE (30 μM) | UTII (0.01 μM) | 109 mM K+PSS |
|---|---|---|---|
| Control | 4.15 ± 0.42 | 1.88 ± 0.31 | 4.57 ± 0.37 |
| UTII | 2.25 ± 0.43* | 0.65 ± 0.13* | 4.27 ± 0.43 |
| VO | 2.86 ± 0.29* | 1.70 ± 0.13 | 1.99 ± 0.36* |
| VO+UTII | 2.23 ± 0.25* | 1.37 ± 0.15 | 3.73 ± 1.12 |
p<0.05 vs. Control