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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Drug Alcohol Depend. 2010 Jun 16;112(1-2):9–17. doi: 10.1016/j.drugalcdep.2010.04.019

Table 3.

Mean values for selected aspects of expression and course of alcoholism: U.S. adults 18 years of age and older with lifetime DSM-IV alcohol dependence, by type of lifetime psychopathologya

Aspects of clinical presentation/course Type of lifetime psychopathologya
Neither internalizing nor externalizing (NINE) Internalizing only (IO) Externalizing only (EO) Both internalizing and externalizing (BIE)
Male (n=1,422) Female (n=514) Male (n=814) Female (n=921) Male (n=252) Female (n=67) Male (n=486) Female (n=305)
Average daily volume of ethanol intake (oz.)b 4.6 (0.2) 2.3 (0.2) 4.8 (0.3) 2.7 (0.2) 10.3 (1.8) c,d 3.2 (0.5) 8.2 (0.8) c,d 6.5 (1.0) c,d,e
Overall freq. drinking b 231.8 (4.3) 192.7 (6.7) 243.4 (5.5) 200.8 (4.8) 276.2 (8.0) c,d 252.7 (19.5) c,d 262.3 (6.9) c,d 249.5 (8.8) c,d
Freq. drinking 5+ drinks b 186.5 (4.7) 119.2 (6.7) 197.0 (6.5) 126.1 (5.6) 249.4 (9.2) c,d 172.9 (21.4) c,d 229.2 (7.5) c,d 196.5 (10.3) c,d
Largest quantity of drinks consumed in a single dayb 16.0 (0.3) 8.9 (0.3) 14.7 (0.5) c 9.3 (0.3) 20.5 (1.2) c,d 10.1 (0.7) 19.6 (0.7) c,d 13.8 (0.7) c,d,e
Mean age at onset of dependence 24.5 (0.3) 24.8 (0.5) 24.5 (0.3) 25.1 (0.4) 21.3 (0.5) c,d 22.7 (1.1) d 22.5 (0.4) c,d 21.6 (0.5) c,d
Mean years from initiation of drinking to onset of dependence 7.6 (0.3) 7.1 (0.4) 7.3 (0.3) 7.2 (0.3) 6.3 (0.5) c 6.8 (1.1) 7.0 (0.4) 5.7 (0.4) c,d,
Density of familial alcoholism 0.26 (0.01) 0.32 (0.02) 0.31 (0.02) c 0.44 (0.02) c 0.45 (0.03) c,d 0.59 (0.07) c,d 0.51 (0.03) c,d 0.64 (0.04) c,d
# lifetime AUD symptoms 11.6 (0.2) 10.1 (0.3) 13.3 (0.3) c 11.1 (0.3) c 16.0 (0.6) c,d 16.4 (1.5) c,d 17.0 (0.4) c,d 16.9 (0.5) c,d
% initiating drinking <15 12.8 (1.1) 13.3 (1.9) 13.9 (1.4) 13.9 (1.6) 37.3 (4.1) c,d 33.1 (7.0) c,d 34.6 (2.5) c,d 40.3 (3.3) c,d
% with multiple episodes of dependence 23.8 (1.6) 21.0 (2.4) 29.2 (1.9) c 25.7 (1.8) 32.3 (4.5) 41.6 (7.2) c,d 39.8 (2.5) c,d 36.2 (3.5) c,d
% in full remission from dependence at Wave 1 43.3 (1.6) 40.6 (2.8) 46.7 (2.1) 47.0 (2.0) 47.2 (3.9) 50.1 (8.1) 41.4 (2.6) 41.1 (3.6)
% ever treated/participated in 12-step program 21.9 (1.3) 11.9 (1.5) 22.5 (1.6) 16.5 (1.5) c 36.4 (3.9) c,d 44.5 (6.7) c,d 39.6 (2.7) c,d 38.8 (3.4) c,d

Note: Figures in parentheses are standard errors of percentages. Shaded cells indicate mean values that are significantly different (p<.05) for males and females.

a

Internalizing = major depressive disorder, bipolar 1 or 2 disorder, dysthymia, panic disorder with or without agoraphobia, specific and social phobia, generalized anxiety disorder; externalizing = illicit drug dependence, ASPD

b

During period of heaviest consumption

c

Significantly different (p<.05) than value for neither internalizing nor externalizing

d

Significantly different (p<.05) than value for internalizing only

e

Significantly different (p<.05) than value for externalizing only