Table 1.

Patient CAE clinical information

Pt	Gender	Age at onset (years)	Age at scan (years)	Medicationa	EEGb	Reported sz frequency at time of onset	Reported sz frequency at time of scans	# Szs during EEG/fMRId	#CPT Runsc	#RTT Runsc	#Fixation Runsc
1	F	8	14	Lamotrigine/none	Normal 8–9 Hz background. Frequent generalized frontal predominant 1.5 to 3.5 Hz spike-wave.	10/day	10/day	1	4	0	2
2	F	11	12	none	Normal 10 Hz background. Frequent generalized frontal predominant 3 Hz spike-wave.	240/day	240/day	9	10	0	8
3	M	6	10	Lamotrigine/none	Normal 9 Hz background. Bursts of symmetrical large amplitude 3 Hz spike-wave.	1/week	none	3	4	3	0
4	F	4	13	Ethosuximide/none	Normal 9 Hz background. Frequent generalized frontal predominant 3.5 to 4 Hz spike-wave.	1–2/week	1/week	6	2	2	0
5	M	13	13	none	Normal 9 Hz background. Frequent generalized frontal predominant 3 Hz spike-wave.	15/day	1/day	7	4	4	5
6	F	9	12	Valproate/none	Normal background of alpha activity with intermixed theta. Frequent generalized 3 Hz spike-wave.	100/day	5/day	3	4	4	0
7	M	10	15	none	Normal 9–10 Hz background. Frequent 3 Hz spike-waves lasing 3–5 sec.	none	none	7	4	4	0
8	F	5	6	none	Normal 7–8 Hz background. Frequent 3–3.5 Hz spike- waves lasing 5–12 sec.	none	5/day	18	5	1	4
9	F	6	8	Ethosuximide/none	Normal 10 Hz background. Generalized 3 Hz spike-wave lasting 8 sec.	10–50/day	120/day	6	0	0	4

^aMedication being taken before scan/medication at time of scan (see Methods).

^bEEG at time of recruitment obtained from patient clinical EEG records. Similar EEG recordings were obtained for each patient during EEG-fMRI.

^cScans were repeated on different days for some patients. Several (up to 4) data runs were performed on each day.

^dTotal number of seizures across all scans and runs.

Abbreviations: Pt = patients, sz = seizure