Table 8.
Comparison of
,
and
plasma clearances from three sources. Note that
is more accurate than
, yet is within the CI for constant infusion and 24 h AUC
| Units: | ml/min/1.73 m2 | Percent | ||||
|---|---|---|---|---|---|---|
| Source: | Florijn et al. | This paper | Moore et al. | This paper | ||
| E 2 approximation: | 5 min injectiona | Constrainedb | 4 h AUCc | Constrained | ||
method: |
Constant infusion | Tk-GV | 24 h AUC | Tk-GV | ||
| 95% CI | 95% CI | |||||
|
5.1 | 6.1 | 4.7 to 7.6 | 10.0 | 10.6 | 8.6 to 12.7 |
|
8.3 | ~7.3 | – | 7.6 | ~7.0 | – |
|
13.4 | – | – | 17.6 | – | – |
aInulin,
b 99mTc-DTPA,
with constraints
and
c
51Cr-EDTA, from numerical integration of
, then mono-exponential extrapolation



