TABLE 3.

Genes with significantly different expression profiles in L. lactis strains NZ9000 and MG1363 grown in GCDM or GM17 medium^a

Functional category and gene	Fold change in expression
	GCDM	GM17	Global
Carbohydrate transport and metabolism
Maltose, dextrose, and amylose
mapA	−75.73	−32.52	−49.63
dexA	−57.91	−16.42	−30.83
amyY	−58.69	−13.23	−27.87
malE	−15.10	−15.11	−15.11
agl	−29.56	−4.67	−11.75
maa	−27.98		−10.30
dexC	−17.36	−6.02	−10.23
malF	−12.46	−5.24	−8.81
malR	−2.10	−4.31	−3.01
malG	−2.52		−2.30
apu	−11.74		−6.26
glgP	−10.67	−5.27	−6.99
llmg_1868	−4.77		−3.46
Cellobiose PTS system
ptcA	−2.41	−1.97	−2.18
ptcC	49.84	13.25	25.69
bglA	41.68		21.03
Mannitol PTS system
mtlR	−55.37		−16.32
mtlA	−14.34	−16.08	−15.31
mtlF	−7.76
mtlD	−5.53
Trehalose metabolism
llmg_0454	−2.53		−2.19
trePP	−2.35		−2.96
Other
msmK	−5.24	−13.96	−8.55
Amino acid transport and metabolism
pepN	−32.40	−8.65	−16.74
argG	−2.86
argH	−2.54
argE	−2.22
argB	−2.17
argF	−2.11
gltS	−2.09
Nucleotide metabolism
nrdH	3.05	1.55	2.18
nrdI	3.04
nrdE	2.89	1.97	2.38
nrdF	2.69
nrdG	2.22
nucA	4.01
napC	12.81		5.62

^aRatios of the intensity of the respective gene spots on the microarray slides are indicated. Positive values indicate upregulation in NZ9000, and negative values indicate downregulation (relative to MG1363).