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. Author manuscript; available in PMC: 2011 Apr 15.
Published in final edited form as: Neuroimage. 2010 Jan 18;50(3):1004–1016. doi: 10.1016/j.neuroimage.2010.01.041

Table 1.

The table summarizes cortical group statistics within cortical regions that significantly SCCA-correlate in toto with white matter integrity. The significantly affected volume within each anatomical area is reported as Vol along with the minimum p-value in that region. Voxel-wise Wilcoxon rank-sum statistics were used. The raw p-values were then FDR corrected with significance selected at corrected p-value < 0.05 with a minimum cluster size of 20 mm3. The AD-Elderly test were performed using the AD-SCCA regions as a mask. The FTD-Elderly and FTD-AD tests used the FTD-SCCA regions as a mask. No highlighting indicates all contrasts are significant; blue highlighting indicates only the FTD contrasts; yellow highlighting indicates that both the contrasts with elderly are significant; gray highlighting indicates only the FTD-Elderly contrasts reach significance; pink indicates AD-Elderly alone is significant.

Cortical anatomy AD < ELD FTD < ELD FTD < AD
Vol. (mm3) Min p Vol. Min p Vol. Min p
L. Cingulate Gyrus 616 0.00001 1928 0.00002 1024 0.00187
R. Cingulate Gyrus 2960 0.00001 2600 0.00004 1096 0.01882
R. Insula 1616 0.00031 488 0.00001 416 0.00593
L. Sup. Frontal Gyrus 136 0.01309 3448 0.00002 2208 0.00890
R. Sup. Frontal Gyrus 1880 0.00026 2776 0.00014 912 0.01882
R. Mid. Frontal Gyrus 1296 0.00058 1328 0.00012 384 0.01533
R. Inf. Frontal Gyrus 1480 0.00022 1864 0.00000 1736 0.00073
R. Orbital Frontal Gyrus 560 0.00214 1840 0.00001 1008 0.00318
R. Precentral Gyrus 912 0.00046 264 0.00009 152 0.01700
L. Temporal Pole 296 0.00014 — — — —
R. Temporal Pole 184 0.00996 — — — —
R. Parahippocampal Gyrus 1288 0.00001 — — — —
L. Sup. Parietal/Precuneus 96 0.00000 — — — —
R. Sup. Parietal/Precuneus 720 0.00001 — — — —
R. Postcentral Gyrus 856 0.00106 — — — —
R. Sup. Temp. Gyrus 1376 0.00002 40 0.00803 — —
L. Infero. Temp. Gyrus 72 0.00122 192 0.00087 — —
R. Infero. Temp. Gyrus 4720 0.00004 504 0.00008 — —
L. Parahippocampal Gyrus 680 0.00000 880 0.00005 — —
R. Inf. Parietal Lobe 6216 0.00002 200 0.00060 — —
L. Sup. Temp. Gyrus — — 760 0.00044 — —
L. Inf. Parietal Lobe — — 440 0.00212 — —
L. Postcentral Gyrus — — 264 0.00478 — —
L. Insula — — 888 0.00001 288 0.02652
L. Frontal Pole — — 1392 0.00011 1040 0.01615
R. Frontal Pole — — 2032 0.00016 592 0.01789
L. Mid. Frontal Gyrus — — 3984 0.00000 2336 0.00098
L. Inf. Frontal Gyrus — — 2592 0.00000 1576 0.00079
L. Orbital Frontal Gyrus — — 5000 0.00001 3464 0.00031
L. Precentral Gyrus — — 832 0.00000 336 0.01615