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. Author manuscript; available in PMC: 2011 Apr 15.
Published in final edited form as: Neuroimage. 2010 Jan 18;50(3):1004–1016. doi: 10.1016/j.neuroimage.2010.01.041

Table 2.

The table summarizes white matter group statistics within white matter regions that significantly SCCA-correlate in toto with cortical thickness. Voxel-wise Wilcoxon rank-sum statistics were used. The raw p-values were then FDR corrected with significance selected at corrected p-value < 0.05 with a minimum cluster size of 20 mm3. The AD-Elderly test were performed using the AD-SCCA regions as a mask. The FTD-Elderly and FTD-AD tests used the FTD-SCCA regions as a mask. White matter regions in FTD focus in the left anterior corona radiata, the splenium, the genu, the bilateral uncinate (left in particular) and the inferior longitudinal fasciculus. In contrast, AD more strongly involves right superior longitudinal fasciculus and the mid-body of the callosum, along with anterior, right temporal lobe white matter tracts and supplemental motor area. No highlighting indicates all contrasts are significant; blue highlighting indicates only the FTD contrasts; yellow highlighting indicates that both the contrasts with elderly are significant; gray highlighting indicates only the FTD-Elderly contrasts reach significance; pink indicates AD-Elderly alone is significant.

White matter anatomy AD < ELD FTD < ELD FTD < AD
Vol. (mm3) Min p Vol. Min p Vol. Min p
L. corticospinal Tract 1696 0.00020963 608 1.01E-06 280 0.00064981
R. corticospinal Tract 2000 0.000158966 344 0.000141561 48 0.0157923
L. inferior longitudinal fasciculus 24 0.0206661 424 7.34E-05 24 0.0108836
R. inferior longitudinal fasciculus 1952 0.000357449 720 1.42E-05 280 0.015609
L. inferior fronto-occipital fasciculus 968 0.000174463 3728 1.13E-06 1408 3.39E-05
R. inferior fronto-occipital fasciculus 2224 9.87E-05 2432 2.80E-06 1512 0.00293112
L. uncinate fasciculus 160 0.000229537 536 8.94E-07 424 0.00013715
R. uncinate fasciculus 256 0.00220811 216 0.000312626 216 0.00385225
Anterior corpus callosum 5368 4.90E-05 8088 2.38E-07 5976 0.000945151
Posterior corpus callosum 3824 2.44E-06 1744 1.67E-06 376 0.00135899
Mid-body corpus callosum 480 8.12E-05 5208 0.000202656 232 0.01732
L. superior longitudinal fasciculus 992 0.000229537 — — — —
R. superior longitudinal fasciculus 408 0.000822663 480 0.00615722 — —