Table 1. Inhibition of [3H]dopamine uptake into chromaffin granule.
IC50 values were determined from inhibition studies of [3H]dopamine uptake into chromaffin granule ghosts, as described in the Materials and Methods section.
| Compound IC50 of [3H]dopamine transport (nM) +/− SEM | |
|---|---|
| Reserpine | 37 +/− 15 |
| BAMER | 73 +/− 57 |
| AIPPMER | 83 +/− 16 |
| IAPEGlyMER | 200 +/− 67 |
| Tetrabenazine | 48 +/− 3 |
| TBZ-AIPP | 2100 +/− 450 |