Table 4.
Recovery blood pressure and cardiovascular outcomes, multivariable models
Blood Pressure Parameter | Cardiovascular disease events | Coronary heart disease events | ||
---|---|---|---|---|
Models using continuous blood pressure variables (per SD increment in BP) | ||||
Post-Exercise recovery Systolic BP | Adjusted HR (95% CI) | P-value | Adjusted HR (95% CI) | P-value |
Age and sex-adjusted | 1.33 (1.18–1.51) | <0.0001 | 1.30 (1.13–1.51) | 0.0003 |
+ Rest Systolic BP and Diastolic BP | 1.16 (0.99–1.35) | 0.07 | 1.14 (0.95–1.36) | 0.15 |
+ Multivariable | 1.11 (0.95–1.31) | 0.19 | 1.08 (0.90–1.29) | 0.42 |
+ Exercise Tolerance Test Variables | 1.16 (0.98–1.38) | 0.09 | 1.12 (0.92–1.36) | 0.26 |
Post-Exercise recovery Diastolic BP | ||||
Age and sex-adjusted | 1.22 (1.06–1.40) | 0.006 | 1.20 (1.02–1.41) | 0.030 |
+ Rest Systolic BP and Diastolic BP | 1.08 (0.92–1.27) | 0.34 | 1.07 (0.89–1.28) | 0.48 |
+ Multivariable | 1.10 (0.94–1.29) | 0.24 | 1.09 (0.91–1.30) | 0.37 |
+ Exercise Tolerance Test Variables | 1.08 (0.92–1.28) | 0.35 | 1.03 (0.85–1.24) | 0.80 |
Models using categorical blood pressure variables (>80th percentile) | ||||
Post-Exercise recovery Systolic BP | Adjusted HR (95% CI) | P-value | Adjusted HR (95% CI) | P-value |
Age and sex-adjusted | 1.56 (1.18–2.05) | 0.002 | 1.58 (1.15–2.17) | 0.004 |
+ Rest Systolic BP and Diastolic BP | 1.11 (0.80–1.53) | 0.53 | 1.17 (0.80–1.69) | 0.42 |
+ Multivariable | 1.03 (0.74–1.43) | 0.88 | 1.03 (0.70–1.51) | 0.89 |
+ Exercise Tolerance Test Variables | 1.16 (0.81–1.66) | 0.39 | 1.17 (0.78–1.76) | 0.46 |
Post-Exercise recovery Diastolic BP | ||||
Age and sex-adjusted | 1.75 (1.33–2.30) | <0.0001 | 1.79 (1.31–2.45) | 0.0003 |
+ Rest Systolic BP and Diastolic BP | 1.43 (1.04–1.97) | 0.03 | 1.50 (1.04–2.17) | 0.03 |
+ Multivariable | 1.44 (1.04–2.00) | 0.03 | 1.52 (1.04–2.21) | 0.03 |
+ Exercise Tolerance Test Variables | 1.53 (1.08–2.18) | 0.02 | 1.58 (1.05–2.36) | 0.03 |
ETT indicates Exercise Tolerance Test. Covariates included in the multivariable and ETT models are detailed in Table 3.