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. 2010 Oct;27(10):1853–1863. doi: 10.1089/neu.2010.1339

Table 3.

Physiological Variables During the Hyperoxia (HO) Test

 
 Steady-state changes with HO
 
  
  
 p Value
  Baseline (mean ± standard error) HO (mean ± standard error) HO test (baseline versus HO) Exam time Interaction (HO test × exam) HO test for exams 1–5 versus 6–10a HO test for exams 6–10 versus 11–15a HO test for exams 1–5 versus 11–15a
Intracranial pressure (mm Hg) 19.6 ± 0.5 18.0 ± 0.4 <0.0001 .0472 .3260      
Mean arterial pressure (mm Hg) 92.7 ± 0.6 93.4 ± 0.7 .1018 <0.0001 .0277 .0004 .2695 .1431
Jugular venous o2 saturation (%) 71.9 ± 0.6 78.2 ± 0.6 <0.0001 .1217 .3423      
Jugular venous Po2 (mm Hg) 44 ± 1 54 ± 1 <0.0001 .5604 .3940      
Brain tissue Po2 (mm Hg) 27.8 ± 2.5 60.2 ± 4.2 <0.0001 .2745 .0448 .6949 .7313 .5563
End-tidal co2 (mm Hg) 34.7 ± 0.3 32.6 ± 0.3 <0.0001 <0.0001 .3748      
Inspired o2 fraction .41 ± .12 .99 ± .10            
Arterial Po2 (mm Hg) 151 ± 3 401 ± 7 <0.0001 <0.0001 .0323 <0.0001 .8614 .0001
Arterial Pco2 (mm Hg) 37.0 ± 0.3 36.1 ± 0.2 .0024 .2749 .3054      
Flow velocity (cm/sec): Left 74.5 ± 1.5 71.8 ± 1.4 <0.0001 <0.0001 .0845      
Flow velocity (cm/sec): Right 72.3 ± 1.3 69.6 ± 1.3 <0.0001 <0.0001 .4769      
Autoregulatory index: Left 2.6 ± 0.8 3.0 ± 0.9 <0.0001 .0001 .4745      
Autoregulatory index: Right 2.6 ± 0.8 3.1 ± 1.0 <0.0001 .0015 .2615      
a

For Pbto2, the comparisons are between exams 1–4, exams 5–8, and exams 9–12.