Table 4.

Adjusted odds ratios stratified by gender with corresponding 95% confidence intervals associated with various smoking exposures

Variable	Males						Females
	Colorectal Cases		Control Subjects		Adjusted Odds Ratio*		Colorectal Cases		Control Subjects		Adjusted Odds Ratio*
	N	(%)	N	(%)	OR	95% Confidence Interval	N	(%)	N	(%)	OR	95% Confidence Interval
Smoking Status
Never	274	(42.9%)	748	(39.2%)	1.00	Referent	471	(78.0%)	1,307	(72.9%)	1.00	Referent
Former Smoker	127	(19.9%)	324	(17.0%)	1.42	1.01 – 1.98	29	(4.8%)	88	(4.9%)	0.99	0.61 – 1.59
Current Smoker	238	(37.2%)	835	(43.8%)	0.92	0.68 – 1.23	104	(17.2%)	399	(22.2%)	0.74	0.56 – 0.97
Years Smoked
Never Smoker	274	(42.7%)	734	(38.2%)	1.00	Referent	471	(77.9%)	1,306	(72.7%)	1.00	Referent
1–27 Years	87	(13.6%)	233	(12.1%)	1.23	0.85 – 1.77	78	(12.9%)	311	(17.3%)	0.70	0.52 – 0.95
28–41 Years	120	(18.7%)	417	(21.7%)	0.88	0.63 – 1.23	49	(8.1%)	146	(8.1%)	0.98	0.68 – 1.41
> 41 Years	161	(25.1%)	537	(28.0%)	1.01	0.74 – 1.38	7	(1.2%)	33	(1.8%)	0.67	0.27 – 1.67
Pack-Years
Never Smoker	274	(43.7%)	734	(39.1%)	1.00	Referent	471	(78.2%)	1,306	(73.2%)	1.00	Referent
1–24 Pack-Years	84	(13.4%)	249	(13.3%)	1.12	0.78 – 1.62	78	(13.0%)	278	(15.6%)	0.82	0.60 – 1.10
25–45 Pack-Years	123	(19.6%)	409	(21.8%)	1.00	0.72 – 1.39	34	(5.6%)	148	(8.3%)	0.62	0.40 – 0.95
> 45 Pack-Years	146	(23.3%)	483	(25.8%)	1.02	0.74 – 1.40	19	(3.2%)	53	(3.0%)	1.19	0.67 – 2.11
Lifetime Tar Grams♪
Never Smoker	65	(37.6%)	216	(37.4%)	1.00	Referent	290	(86.6%)	920	(83.7%)	1.00	Referent
1–3,133 Grams	35	(20.2%)	92	(15.9%)	1.41	0.83 – 2.38	22	(6.6%)	82	(7.5%)	0.98	0.56 – 1.72
3,133–8,989	32	(18.5%)	117	(20.3%)	1.05	0.62 – 1.76	13	(3.9%)	69	(6.3%)	0.62	0.30 – 1.27
> 8,989	41	(23.7%)	152	(26.3%)	1.05	0.64 – 1.71	10	(3.0%)	28	(2.5%)	1.33	0.57 – 3.08

^*Adjusted for race, age, gender, body mass index, county of residence, and other tobacco use.

^♪Lifetime Tar Grams = Brand Specific Tar Level * (Cigs/Day * 365) * Years