Table 1. Disease severity among 138 episodes of Streptococcal dysgalactiae subsp. equisimilis bacteremia, Finland, 1995–2004*.
Disease severity | No. (%) common emm types, n = 97 | No. (%) rare emm types, n = 41 | Odds ratio (95% CI) | p value† |
---|---|---|---|---|
30-day mortality rate | 11 (11) | 12 (29) | 3.2 (1.3–8.1) | 0.01 |
Patient admitted to ICU | 5 (5) | 6 (15) | 3.2 (0.9–11) | 0.084 |
Patient death or ICU treatment | 12 (12) | 15 (37) | 4.1 (1.7–9.8) | 0.001 |
Hypotension‡ | 13 (13) | 10 (24) | 2.1 (0.8–5.2) | 0.113 |
DIC§ | 2 (2) | 6 (15) | 8.1 (1.6–42.3) | 0.009 |
Multiorgan failure | 2 (2) | 4 (10) | 5.1 ( 0.9–29.2) | 0.064 |
STSS¶ | 2 (2) | 4 (10) | 5.1 ( 0.9–29.2) | 0.064 |
*CI, confidence interval; ICU, intensive care unit; DIC, disseminated intravascular coagulation; STSS, streptococcal toxic shock syndrome. Patients who had both clinical data and isolates available. †χ² test or Fisher exact test as appropriate. ‡Hypotensive (BP <90 mm Hg) at least once 0–2 days after positive blood culture. §Thrombocyte count <100 x 109/L. ¶The definition of STSS was based on a consensus definition, including identification of β-hemolytic streptococci from a normally sterile site, septic shock, and multiorgan failure.