Table 1. Selected characteristics and results of randomized controlled studies examining the effects computerized and internet-based cognitive behaviour therapy for adult depression and anxiety disorders.
Study | Conditions | N | g | NNT | Bias Risk | F-U | Adhere/Satisf |
MAJOR DEPRESSION | |||||||
Andersson, 200522 | iCBT + therapist support > waitlist + discussion group | 75 | 0.87 | 2.16 | 0 | 26w | 63/- |
Kessler, 200923 | iCBT + therapist support > TAU by GP | 297 | 0.61 | 2.99 | 0 | 16w | 73/- |
Perini, 200924 | iCBT + therapist support > waitlist | 48 | 0.56 | 3.25 | 1 | - | 74/82 |
Selmi 199025 | cCBT > waitlist | 36 | 1.26 | 1.59 | 2 | 9w | 100/- |
Titov 201026 | iCBT + therapist support > waitlist | 141 | 0.99 | 1.94 | 1 | - | 70/87 |
Wright 200527 | cCBT + therapist support > waitlist | 45 | 1.10 | 1.77 | 1 | 26w | 87/- |
PANIC DISORDER | |||||||
Carlbring, 200128 | iCBT > waitlist | 41 | 0.99 | 1.94 | 1 | - | 80/85 |
Carlbring, 2006 29 | iCBT > waitlist | 60 | 1.13 | 1.74 | 0 | 39w | 80/97 |
Klein, 2001 30 | iCBT > Self-monitoring control | 23 | 0.39 | 4.59 | 2 | - | 90/- |
Klein, 200631 | iCBT > Information control | 55 | 1.49 | 1.41 | 1 | 13w | 90/- |
Richards, 200632 | iCBT > Information control | 32 | 0.74 | 2.50 | 0 | 13w | 82/- |
Wims 201033 | iCBT + therapist support > waitlist | 59 | 0.28 | 6.41 | 1 | 4w | 79/- |
SOCIAL PHOBIA | |||||||
Andersson, 200634 | iCBT > waitlist | 64 | 0.76 | 2.44 | 0 | 52w | 56/- |
Berger et al. 200935 | iCBT > waitlist | 52 | 0.64 | 2.86 | 1 | - | 90/85 |
Botella et al. 200936 | iCBT > waitlist | 52 | 1.07 | 1.82 | 2 | 52w | 48/- |
Carlbring, 200737 | iCBT > waitlist | 57 | 1.07 | 1.82 | 1 | 52w | 93/- |
Furmark et al 200938 | iCBT + therapist support > waitlist | 120 | 0.67 | 2.75 | 0 | 52w | 97/70 |
Titov, 2008 I39 | iCBT + therapist support > waitlist | 105 | 0.94 | 2.02 | 1 | 26w | 78/100 |
Titov, 2008 II40 | iCBT + therapist support > waitlist | 88 | 1.18 | 1.68 | 1 | 26w | 81/100 |
Titov, 2008 III41 | iCBT + therapist support > waitlist | 98 | 1.02 | 1.89 | 1 | - | 77/- |
GAD | |||||||
Titov 200942 | iCBT + therapist support > waitlist | 48 | 1.08 | 1.81 | 1 | - | 75/85 |
Robinson 201043 | iCBT + therapist support > waitlist | 150 | 1.13 | 1.74 | 1 | - | 74/87 |
N, number randomized; g, Hedges g; NNT number needed to treat; Bias risk (0 = no risk, 5 =  high risk) inadequacy of sequence generation, no allocation concealment, inadequate blinding, missing data not addressed, selective reporting; F-U, follow-up in weeks; Adhere/satisfaction, percent adhering to whole course/percent satisfied with course; iCBT, CBT over the internet; cCBT, CBT over computer in clinic; GAD, Generalized Anxiety Disorder.