Figure 5. FES as a function of 
–
vs. 
contacts (top panels) and of 
–
vs. 
contacts (bottom panels) at T
= 0.969, T
= 0.998 and T
= 1.021.
FES are obtained by reweighting the structure-based potential PTMetaD simulation. Isoenergy lines are drawn every 
. In dashed lines, projection of the relevant part of the all-atom explicit-solvent unfolding simulations at 700K (blue and red) and 500K (yellow).