Figure 7. Effect of in vivo lethal toxin challenge on O₂ ⁻ generation in the absence and presence of the NADPH oxidase inhibitor apocynin pretreatment (80 µg/ml) in drinking water for 6 days.

A: Representative images depicting DHE fluorescent intensity in murine cardiomyocytes following exposure of LeTx (2 µg/g b.w., i.p.) for 18 hrs; B: Pooled data of superoxide production. Mean ± SEM, n = 75–100 cells per group. * p<0.05 vs. C57BL/6J group, #p<0.05 vs. C57BL/6J+LeTx group in the absence of apocynin.