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. 2010 Oct 13;5(10):e13335. doi: 10.1371/journal.pone.0013335

Figure 12. Effect of in vivo lethal toxin (LeTx) exposure on ER stress and autophagy markers in murine hearts.

Figure 12

Adult male C57BL/6J mice were treated with LeTx (2 µg/g b.w., i.p.) for 18 hrs. A: BIP expression; B: Phospho-eIF2α-to- eIF2α ratio; C: Beclin-1 expression; and D: LC3-II-to-tubulin ratio; Insets: Representative gel blots depicting expression of BIP, pan and phospho-eIF2α, Beclin-1, LC3 and α-tubulin (loading control) using specific antibodies. Mean ± SEM, n = 5 – 6 mice. * p<0.05 vs. C57BL/6J group without LeTx treatment.