Table 4. Frequency of cryoprotectant reagents found as bound ligands in JCSG structures.
Values in parentheses correspond to occurances in all of the other structures in the PDB. These numbers are obtained from structures that report the use of these compounds in the crystal-growth conditions in their headers.
| Cryo reagent† | No. of times used in crystallization/cryoprotective conditions | No. of times observed in structures | % observed |
|---|---|---|---|
| EDO | 348 (888) | 284 (184) | 81.6 (20.7) |
| GOL | 302 (3079) | 167 (723) | 55.3 (23.5) |
| MPD | 106 (2558) | 47 (373) | 44.3 (14.6) |
| PEG 200 | 78 | 44 | 56.4 |
| PEG 400 | 70 | 21 | 30.0 |
†
Three-letter codes: EDO, ethylene glycol; GOL, glycerol; MPD, 2-methyl-2,4-pentanediol.