Table 4.
Parameter values for ion movement | |||||
---|---|---|---|---|---|
Physical constants | |||||
R | 8.315 J mol−1 K−1 | T | 310 K | F | 96490 C mol−1 |
Whole cell conductance’s | |||||
gCl | 31.4 nS * | gK | 14 nS ** | ||
Pump Densities | |||||
αNaK | 2.236 × 10−17 mol | αNKCC | 3.2 × 10−17 mol | ||
Volumes | |||||
w0 | 10− 12 L | wL/w0 | 0.02 | ||
Water permeabilities | |||||
LPa | 1.68 × 10−15 L2 J−1 s−1 | LPb | 2.07 × 10−14 L2 J−1 s−1 | ||
LPt | 8.4 × 10−17 L2 J−1 s−1 | ||||
Cell properties | |||||
Cm | 10−11F | x/w0 | 30.7 mM | ||
Electrical parameters | |||||
Rtight | 6.8 × 108 ohms | Rcell | 0 | gt,Na | 0.955 |
Ionic valence | |||||
zCl | −1 | zK | +1 | zNa | +1 |
zCa | +2 |
from Arreola et al. (1996),
from Thompson and Begenisich (2006), other parameters are physical constants or model fits chosen to give the correct steady state concentrations and membrane potentials.