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. 2010 Mar;60(3-2):229–237. doi: 10.1016/j.jinf.2010.01.003

Table 2.

Frequency of symptoms and physical findings on admission in patients diagnosed with primary, secondary and children and adults.

Variables Primary infection (N = 67a) Secondary infection (N = 283) P Children 5–15 years (N = 132a) Adult ≥15 years (N = 218) P
Age (yr)b 12.2 (5.3–51.7) 20.6 (5.5–73.6) <0.001 11.2 (5.3–15.0) 28.1 (15.5–73.7)
Male/female 44/23 180/103 80/52 144/74
Body temperature (°C)b 38.9 (38.0–39.9) 39.0 (38.0–42.0) 39.0 (38.0–42.0) 39.0 (38.0–40.0)
Pulse pressure (mmHg)b 30.0 (30.0–60.0) 40.0 (20.0–60.0) <0.001 30.0 (20.0–55.0) 40.0 (20.0–60.0) <0.001
Heart rate (beats/min)b 90.0 (70.0–130.0) 90.0 (66.0–130.0) 95.0 (76.0–130.0) 90.0 (66.0–120.0) <0.001



Symptoms, (%)
 Headache 91.0 94.7 92.4 95.0
 Myalgia 29.9 52.7 0.001 25.8 61.9 <0.001
 Sore throat 32.8 42.4 44.7 38.1
 Backache 20.9 19.1 6.1 27.5 <0.001
 Nausea 20.9 23.7 14.4 28.4 0.003
 Cough 28.4 33.6 31.8 33.0
 Arthralgia 16.4 17.7 10.6 21.6 0.009
 Gastrointestinal symptoms 25.4 13.1 0.022 12.1 17.4



Findings at physical examination, (%)
 Pallor 19.4 17.3 12.1 21.1 0.043
 Dehydration 11.9 13.1 13.6 12.4
 Pharyngitis 40.3 49.5 48.5 47.2
 Lymph nodes 0.0 0.7 1.5 0.0
 Rash 0.0 2.5 0.0 3.2
 Bruises 6.0 4.2 0.8 6.9 0.007
a

One child (age = 4.2 years) was excluded from analysis.

b

Median (range); differences between groups were analyzed with Mann–Whitney tests. Fisher's exact test was used in all dichotomous data. Gastrointestinal symptoms: abdominal pain, diarrhea and constipation.