Table 3.
Axial length percent increase in experimental compared to control eyes.
p* diff | p†, unadjusted difference | p‡, adjusted for IOP exposure | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Strains | N | mean ± sd | bead--control | median | C57 young | C57 old | CD1 | C57 young | C57 old | CD1 |
DBA/2J | 25 | 16.7 ± 10.7% | <0.0001 | 15.8% | 0.14 | 0.0007 | 0.0003 | 0.38 | 0.0026 | 0.0003 |
C57BL/6 younger | 20 | 13.6 ± 14.1% | 0.0004 | 12.4% | 0.02 | 0.01 | 0.07 | 0.08 | ||
C57BL/6 older | 24 | 6.8 ± 7.7 % | 0.0003 | 4.9% | 0.94 | 0.33 | ||||
CD1 | 21 | 5.5 ± 6.7 % | 0.001 | 5.7% |
Sample number (N) and standard deviation (SD).
paired t test;
Mann-Whitney test; from multivariable linear regression,
adjusting for positive integral IOP; for each strain values for 6 and 12 week duration are grouped together.