Table 5.

Axon counts.

		Axon	Axon	Axon Loss	p* diff	Axon Loss	p†, unadjusted difference from			p‡, adjusted for IOP exposure
Strain	N	RE Mean Count	LE Mean Count	mean loss ± SD	bead--control	median loss	C57 young	DBA/2J	C57 old	C57 young	DBA/2J	C57 old
CD1	20	60995 ± 6994	48708 ± 15496	22.5 ± 23.3%	0.0004	16.00%	0.07	0.023	0.003	0.16	0.098	0.017
C57/BL6 younger	24	51064 ± 5045	43045 ± 12802	11.9 ± 19.1%	0.007	6.90%		0.73	0.09		0.83	0.26
DBA/2J	24	60938 ± 5553	54380 ± 13097	10.8 ± 21.0%	0.02	6.20%			0.26			0.43
C57/BL6 older	24	47113 ± 6510	44618 ± 7164	5.2 ± 15.6%	0.22	1.20%

Bead injected (LE) RGC mean and median loss counts were compared to the average values of fellow right eyes (RE) of the same strain followed for the same time period (6 or 12 weeks). Sample number (N), standard deviation (SD), and difference (diff).

^*paired t test;

^†Mann-Whitney test; from multivariable linear regression,

^‡adjusting for positive integral IOP;