Table 6.

RGC layer counts.

		RGC Layer Control	RGC Layer Bead Injected	RGC layer	p* diff	RGC layer	p†, unadjusted difference from			p‡, adjusted for IOP exposure
Strain	N	Mean Count	Mean Count	mean loss ± SD	bead-control	median loss	C57 young	DBA/2J	C57 old	C57 young	DBA/2J	C57 old
CD1	20	3820 ± 232	3247 ± 518	15.0 ± 13.7%	<0.0001	12.70%	0.044	0.02	0.0003	0.029	0.03	<0.0001
C57/BL6 younger	23	4196 ± 406	3851 ± 423	7.5 ± 9.4%	0.007	7.40%		0.31	0.011		0.78	0.024
DBA/2J	24	4121 ± 262	3849 ± 512	6.6 ± 12.8%	0.04	3.80%			0.19			0.081
C57/BL6 older	24	3921 ± 236	3798 ± 260	2.0 ± 7.1%	0.1	1.20%

RGC layer counts comparing mean and median loss in bead-injected (left eye) to the average values of fellow, right eyes of the same strain followed for the same time period (6 or 12 weeks), as well as comparisons of loss among strains of mice. Sample number (N), standard deviation (SD).

^*paired t test;

^†Mann-Whitney test; from multivariable regression,

^‡adjusting for positive integral IOP.