Table 1.
Characteristics of RBD in large case series
| Schenck 1993[9] | Sforza 1997[12] | Olson 2000[8] | Wing 2008[125] | |
|---|---|---|---|---|
| Number of patients | 96 | 52 | 93 | 82 |
| % male | 87.5% | -- | 87% | 82% |
| Mean (SD) age of onset | 52.4 (16.9) | Duration of disease prior to diagnosis: 4.3 (0.9) in idiopathic; 4.9(0.6) with secondary forms |
60.9 (36–84) | 62.1 (12.9) |
| Mean (SD) age at diagnosis | 58.3 (17.4) | 66.2 (2.1) for idiopathic form; 59.9 (1.2) for those associated with neurologic disease |
64.4 (37–85) | 67.4 (10.0) |
| Percent with a history of sleep-related injury | 79.2% | 32% (injury to self) 16% injury to bedpartner) |
80.8% | |
| Percent with sleep disruption | 20.8% | Some degree of sleep disruption present in 100%. Average (SD) sleep efficiency 66.4 (4.4) in idiopathic RBD, 52.4 (2.6) in secondary |
70% (self report) | -- |
| Frequency of dream enacting behaviors | 87.5% | 93% | 98% | |
| Comorbid neurologic diagnoses | 47.9% (composed of degenerative disorders in 23%, narcolepsy in 14%, other in 11%) | 75% | 57% (47% PD, 13% dementia, 26% MSA, 8% narcolepsy, 2% PSP, 2% brainstem stroke) | 19.5% |
| Comorbid or lifetime history of psychiatric disorders | 9.4% | -- | 25.8% (lifetime history) | 33% (lifetime history) |
| Response to clonazepam | Total 90.0% (79.1% complete, 11.1% partial) | 90% | 87% (of the 38 people for whom information was available); 55% complete, 32% partial |
87% of 71 pts |