Table 2.

Medications reported to induce RBD or lack of normal muscle atonia during REM sleep

Class	Medication	RBD or abnormal muscle tone on PSG
SSRI antidepressant	Fluoxetine Paroxetine	Both
SNRI antidepressant	Venlafaxine Mirtazepine	Both
Tricyclic antidepressant	Nortriptyline Imipramine Clomipramine	Worsening of pre-existing RBD or “hyperactivity” in REM
Monoamine oxidase inhibitor	Selegiline
Beta-blocker	Atenolol Bisoprolol	Both
Opioid (with serotonin reuptake inhibition properties)	Tramadol	Witnessed behaviors presumed by medical observer to be RBD